Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004590 | 0.80 | TRPV1 (0.33) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4871010 | 0.73 | NR1H2 (0.34) | — | |
| SCHEMBL6004899 | 0.71 | NR1H2 (0.36) | — | |
| SCHEMBL6004473 | 0.69 | NR1H2 (0.36) | — | |
| SCHEMBL6005072 | 0.68 | NR1H2 (0.37) | — | |
| SCHEMBL6004601 | 0.63 | MAPK11 (0.36) | AADAT | |
| SCHEMBL8603258 | 0.58 | TACR1 (0.39) | — | |
| SCHEMBL8603196 | 0.56 | HTR2B (0.39) | SLC6A3 | |
| SCHEMBL4285494 | 0.56 | SLC6A3 (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL30886485 | 0.53 | RIPK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252807-A1 | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | KALYPSYS, INC. | 2006-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252807-A1 | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | MAPK1, MAP3K1, MAPK4 | AADAT 3946/4885SLC6A3 2833/4885SLC6A4 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.