Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895779 | 0.89 | FGFR2 (0.53) | EGFRPDGFRAPDGFRBFGFR2 | |
| SCHEMBL6004787 | 0.87 | PDGFRB (0.49) | EGFRPDGFRAPDGFRBFGFR2 | |
| SCHEMBL6004575 | 0.86 | PDGFRB (0.48) | EGFRPDGFRAPDGFRBFGFR2 | |
| SCHEMBL3894958 | 0.85 | SRC (0.49) | PDGFRAPDGFRBFGFR2 | |
| SCHEMBL6004713 | 0.84 | KDR (0.48) | EGFRPDGFRAPDGFRBFGFR2 | |
| SCHEMBL6004223 | 0.84 | PDGFRA (0.48) | PDGFRAPDGFRBFGFR2 | |
| SCHEMBL6005261 | 0.83 | KDM4E (0.49) | FGFR2 | |
| SCHEMBL6004736 | 0.83 | KDM4E (0.48) | PDGFRAFGFR2 | |
| SCHEMBL6005269 | 0.83 | FGFR2 (0.47) | PDGFRAPDGFRBFGFR2 | |
| SCHEMBL6004765 | 0.82 | FGFR2 (0.45) | PDGFRAPDGFRBFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |