Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 12/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706378 | 0.99 | CHEK2 (0.55) | CHEK2LTA4HHRH2HRH1AURKB | |
| Hydrochloric Acid SCHEMBL6560096 | 0.97 | CHEK2 (0.54) | CHEK2LTA4HHRH2HRH1AURKB | |
| SCHEMBL3866051 | 0.87 | CHEK2 (0.56) | CHEK2LTA4HHRH2HRH1 | |
| Hydrochloric Acid SCHEMBL6561583 | 0.86 | CHEK2 (0.55) | CHEK2LTA4HHRH2HRH1 | |
| SCHEMBL7447377 | 0.85 | LTA4H (0.56) | CHEK2LTA4HHRH2HRH1AURKB | |
| SCHEMBL6560708 | 0.84 | MAPT (0.56) | CHEK2LTA4HHRH2HRH1 | |
| SCHEMBL7335065 | 0.84 | LTA4H (0.54) | CHEK2LTA4H | |
| SCHEMBL6053346 | 0.84 | CHEK2 (0.58) | CHEK2LTA4HHRH2HRH1 | |
| Hydrochloric Acid SCHEMBL7328923 | 0.82 | LTA4H (0.53) | CHEK2LTA4H | |
| SCHEMBL6005460 | 0.82 | LTA4H (0.49) | CHEK2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709021-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS FOR THE TREATMENT OF VASOMOTOR SYMPTOMS | ELI LILLY AND COMPANY (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005073204-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS FOR THE TREATMENT OF VASOMOTOR SYMPTOMS | ELI LILLY AND COMPANY (US) | 2005-08-11 | — | — | WO | disclosed |