Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.48 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102043 | 0.89 | KCNQ2 (0.49) | HDAC3HDAC1HDAC2NCOR2KCNQ2 | |
| SCHEMBL30796241 | 0.89 | KCNQ2 (0.49) | HDAC3HDAC1HDAC2NCOR2KCNQ2 | |
| SCHEMBL3093876 | 0.86 | KCNQ2 (0.50) | HDAC3HDAC1HDAC2NCOR2KCNQ2 | |
| SCHEMBL30795882 | 0.86 | KCNQ2 (0.50) | HDAC3HDAC1HDAC2NCOR2KCNQ2 | |
| SCHEMBL27729083 | 0.82 | CYP1A2 (0.49) | HDAC3HDAC1HDAC2KCNQ2KCNQ3 | |
| SCHEMBL3106563 | 0.79 | HDAC1 (0.47) | HDAC3HDAC1HDAC2KCNQ2KCNQ3 | |
| SCHEMBL1829206 | 0.78 | KCNQ2 (0.55) | HDAC3HDAC1HDAC2NCOR2KCNQ2 | |
| SCHEMBL3106936 | 0.77 | ALDH1A1 (0.48) | HDAC3HDAC1HDAC2KCNQ2KCNQ3 | |
| SCHEMBL3106784 | 0.76 | CYP1A2 (0.51) | HDAC3HDAC1HDAC2KCNQ2KCNQ3 | |
| SCHEMBL3113156 | 0.76 | KCNQ2 (0.68) | HDAC3HDAC1HDAC2NCOR2KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | H. LUNDBECK A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | CYP3A43, UGT2B7, CYP3A7 | HDAC3 506/4885HDAC1 775/4885HDAC2 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.