Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.68 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.68 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714674 | 0.90 | CSNK1A1 (0.76) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| SCHEMBL30965100 | 0.85 | CSNK1A1 (0.73) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| SCHEMBL297622 | 0.85 | CSNK1A1 (0.73) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5854599 | 0.84 | CSNK1A1 (0.71) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| SCHEMBL15478263 | 0.81 | CSNK1A1 (0.71) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| SCHEMBL11566235 | 0.81 | CSNK1A1 (0.71) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| SCHEMBL6825869 | 0.81 | CSNK1A1 (1.00) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| SCHEMBL10912947 | 0.80 | MAPT (0.55) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| Water SCHEMBL30473073 | 0.79 | CSNK1A1 (0.97) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| SCHEMBL11985512 | 0.78 | CSNK1A1 (0.68) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53149975-A | — | — | None | — | — | JP | disclosed |
| EP-1207161-B1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-6777410-B2 | SUCH AS 9-(2-METHOXYPHENYL)-3-(1-METHYLETHYL)-(1,3)OXAZOLO-(2,3)ISOINDOLE-2,5(3H,9H)-DIONE; DIABETES AND COMPLICATIONS; OBESITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20040053923-A1 | Novel isoindole derivatives | BANYU PHARMACEUTICAL CO., LTD. | 2004-03-18 | — | — | US | disclosed |
| US-6608098-B1 | Diabetes or obesity, 2-(4-(3-isopropyl-2,5-dioxo-2,3-dihydro-1H-pyrrolo(2,1-a) isoindol-9(5H)-yl)phenoxy)-N-propylacetamide | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1207161-A1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001068610-A1 | IMIDAZOLYLBENZOPHENONE DERIVATIVES | TAISHO PHARMACEUTICAL CO.,LTD (JP) | 2001-09-20 | — | — | WO | disclosed |
| JP-S53149975-A | PREPARATION OF IMIDAZOLYLBENZOPHENONES | TEIJIN LTD | 1978-12-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053923-A1 | Novel isoindole derivatives | GPR119, SLC5A2, SLC5A1 | CSNK1A1 258/4885TYRO3 2236/4885DYRK1B 2156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.