Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390882 | 0.64 | HIF1A (0.53) | HIF1A | |
| SCHEMBL13443047 | 0.59 | HIF1A (0.44) | HIF1A | |
| SCHEMBL1106477 | 0.59 | HIF1A (0.45) | HIF1A | |
| SCHEMBL13443048 | 0.58 | HIF1A (0.35) | HIF1A | |
| SCHEMBL20664871 | 0.57 | HIF1A (0.44) | HIF1A | |
| SCHEMBL23760241 | 0.57 | HIF1A (0.43) | HIF1A | |
| SCHEMBL21591572 | 0.54 | HIF1A (0.39) | HIF1A | |
| SCHEMBL12413756 | 0.53 | POLB (0.46) | HIF1A | |
| SCHEMBL22606405 | 0.53 | HIF1A (0.43) | HIF1A | |
| SCHEMBL7196866 | 0.52 | HIF1A (0.37) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613311-A2 | HIF-1 INHIBITORS | Emory University (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087066-A2 | HIF-1 INHIBITORS | EMORY UNIVERSITY (US) | 2004-10-14 | — | — | WO | disclosed |