Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19427718 | 0.87 | MAPT (0.79) | GAATP53MAPTSMN1; SMN2KMT2A | |
| SCHEMBL5833241 | 0.86 | ALDH1A1 (0.73) | GAAMAPTSMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL2502603 | 0.86 | MAPT (0.71) | GAATP53MAPTSMN1; SMN2KMT2A | |
| SCHEMBL11660471 | 0.86 | MAPT (0.70) | GAATP53MAPTSMN1; SMN2KMT2A | |
| SCHEMBL20357354 | 0.84 | GAA (0.51) | GAATP53MAPTSMN1; SMN2KMT2A | |
| SCHEMBL167053 | 0.84 | GAA (0.67) | GAATP53MAPTSMN1; SMN2KMT2A | |
| SCHEMBL862532 | 0.84 | TSHR (0.70) | GAATP53MAPTSMN1; SMN2KMT2A | |
| SCHEMBL3704664 | 0.84 | GAA (0.61) | GAATP53MAPTSMN1; SMN2KMT2A | |
| SCHEMBL14338700 | 0.83 | MAPT (0.68) | GAATP53MAPTSMN1; SMN2KMT2A | |
| SCHEMBL29826604 | 0.82 | TP53 (0.83) | GAATP53MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353926-B1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOD CONSEILS RECH APPLIC (FR) | 2006-03-08 | — | — | EP | claimed |
| JP-2004533456-A | — | — | 2004-11-04 | — | — | JP | claimed |
| EP-1438039-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-07-21 | — | — | EP | claimed |
| EP-1353926-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2003-10-22 | — | — | EP | claimed |
| WO-2002096348-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-12-05 | — | — | WO | claimed |
| WO-2002055523-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-07-18 | — | — | WO | claimed |
| EP-1353926-B1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOD CONSEILS RECH APPLIC (FR) | 2006-03-08 | — | — | EP | disclosed |
| EP-1438039-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-07-21 | — | — | EP | disclosed |
| EP-1353926-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002096348-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002055523-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-07-18 | — | — | WO | disclosed |