Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841104 | 0.88 | KMT2A (0.62) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL19427718 | 0.87 | MAPT (0.79) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL6005341 | 0.86 | GAA (0.69) | MAPTALDH1A1HTTGAATP53 | |
| SCHEMBL2191052 | 0.86 | HSD17B1 (0.75) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL11660471 | 0.86 | MAPT (0.70) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL30622065 | 0.86 | HSD17B1 (0.75) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL29156543 | 0.85 | MAPT (0.56) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL20373538 | 0.85 | MAPT (0.56) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL19459414 | 0.84 | MAPT (0.54) | MAPTALDH1A1HTTKDM4EGAA | |
| SCHEMBL7284431 | 0.84 | NPSR1 (0.57) | MAPTALDH1A1HTTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230366033-A1 | METHODS FOR TREATING CANCERS WITH INHIBITORS TARGETING THE ROLE OF GRB2 IN DNA REPAIR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-11-16 | — | — | US | disclosed |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2020-11-24 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| US-20150037834-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2015-02-05 | — | — | US | disclosed |
| US-20150037834-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2015-02-05 | — | — | US | disclosed |
| US-8637658-B2 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-28 | — | — | US | disclosed |
| EP-0054513-B1 | PROCESS FOR THE PRODUCTION OF PHOTOGRAPHIC COLOUR IMAGES ACCORDING TO THE SILVER DYE BLEACHING PROCESS, AND PHOTOGRAPHIC MATERIAL USED IN THIS PROCESS | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | disclosed |
| US-4465763-A | OIL SOLUBLE TRIAZINE COMPOUND AND A PHENYL AMINE COUPLER | CIBA GEIGY AG (CH) | 1984-08-14 | — | — | US | disclosed |
| EP-0049711-B1 | PROCESS FOR THE PRODUCTION OF NITRO-AMINO-BENZENES | BAYER AG (DE) | 1984-02-29 | — | — | EP | disclosed |
| US-4404273-A | Process for the production of photographic color images by the silver dye bleach process | CIBA-GEIGY AG (CH) | 1983-09-13 | — | — | US | disclosed |
| EP-0054513-A1 | Process for the production of photographic colour images according to the silver dye bleaching process, and photographic material used in this process | CIBA-GEIGY AG (CH) | 1982-06-23 | — | — | EP | disclosed |
| EP-0049711-A1 | Process for the production of nitro-amino-benzenes | BAYER AG (DE) | 1982-04-21 | — | — | EP | disclosed |
| EP-0029009-A1 | Preparation of pigments | CIBA-GEIGY AG (CH) | 1981-05-20 | — | — | EP | disclosed |
| EP-0012980-A1 | Process for the preparation of 2,5-dialkoxy-aniline-4-sulfonic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-07-09 | — | — | EP | disclosed |
| US-4119622-A | Pyrazolonylazoaniline or aminonaphtyl compounds for copying processes | BASF AKTIENGESELLSCHAFT (DE) | 1978-10-10 | — | — | US | disclosed |
| US-3933887-A | Process for preparing 4-amino-2,5-dialkoxybenzonitriles | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | MAPT 3982/4885ALDH1A1 1315/4885HTT 3985/4885 |
| US-20230366033-A1 | METHODS FOR TREATING CANCERS WITH INHIBITORS TARGETING THE ROLE OF GRB2 IN DNA REPAIR | GRB2, RAD51, MRE11 | MAPT 4193/4885ALDH1A1 3059/4885HTT 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.