Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL988548 | 1.00 | TDP1 (0.83) | — | |
| Propylene Glycol SCHEMBL28349323 | 1.00 | TDP1 (0.83) | — | |
| Propylene Glycol SCHEMBL6812682 | 0.96 | — | — | |
| Propylene Glycol SCHEMBL5908157 | 0.96 | — | — | |
| Propylene Glycol SCHEMBL28966021 | 0.93 | TDP1 (0.71) | — | |
| Propylene Glycol SCHEMBL27397419 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL161401 | 0.91 | TDP1 (1.00) | — | |
| Propylene Glycol SCHEMBL7522896 | 0.91 | TDP1 (1.00) | — | |
| Propylene Glycol SCHEMBL28578 | 0.91 | — | — | |
| Propylene Glycol SCHEMBL724028 | 0.91 | TDP1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425467-A | Personal care compositions comprising silicone based | 迈图高新材料公司 | 2024-01-19 | — | — | CN | claimed |
| EP-3101102-B2 | COMPACTED LIQUID LAUNDRY DETERGENT COMPOSITION | PROCTER & GAMBLE (US) | 2023-12-13 | — | — | EP | claimed |
| CN-116751728-A | Genetically engineered bacterium for converting vitamin D3 into 25-hydroxy vitamin D3, gene, expression vector and application thereof | 浙江惠嘉生物科技股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-116573900-A | Soil stabilizer and preparation method and application thereof | 上海海顾新材料科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116549423-A | Resveratrol dihydric alcohol plastid and preparation method and application thereof | 浙江中医药大学 | 2023-08-08 | — | — | CN | claimed |
| CN-116491680-A | Tea extract and preparation method of electronic cigarette atomized liquid containing tea extract | 四川蜀茶数字科技有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-115227642-A | Metronidazole gel preparation technology | 江苏晨牌邦德药业有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-115176989-A | Transparent curcumin oil solution and preparation method and application thereof | 河南中大恒源生物科技股份有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-114854493-A | Preparation method of Maillard reaction product by using raisin extract | 深圳波顿香料有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-111592575-B | Novel synthesis method of compound arginine diglycoside AFG | 吉林农业大学 | 2021-02-02 | — | — | CN | claimed |
| WO-1988009788-A1 | TOPICAL PRODRUGS FOR TREATMENT OF ACNE AND SKIN DISEASES | MOLECULAR DESIGN INTERNATIONAL, INC. (US) | 1988-12-15 | — | — | WO | claimed |
| EP-0236280-A1 | Injectable pharmaceutical formulations of active principles having general anaesthetic activity | Mazzarella, Basilio (IT) | 1987-09-09 | — | — | EP | claimed |
| US-4677120-A | Topical prodrugs for treatment of acne and skin diseases | MOLECULAR DESIGN INTERNATIONAL (US) | 1987-06-30 | — | — | US | claimed |
| US-4304787-A | TOPICAL | JOHNSON & JOHNSON (US) | 1981-12-08 | — | — | US | claimed |
| US-4129662-A | Retinoic acid derivatives for the treatment of acne | JOHNSON & JOHNSON (US) | 1978-12-12 | — | — | US | claimed |
| US-4126699-A | RETINOIC ACID DERIVATIVES FOR THE TREATMENT OF ACNE | JOHNSON & JOHNSON (US) | 1978-11-21 | — | — | US | claimed |
| US-4126697-A | RETINOIC ACID DERIVATIVES IN THE TREATMENT OF ACNE | JOHNSON & JOHNSON (US) | 1978-11-21 | — | — | US | claimed |
| US-4126698-A | RETINOIC ACID DERIVATIVES IN THE TREATMENT OF ACNE | JOHNSON & JOHNSON (US) | 1978-11-21 | — | — | US | claimed |
| US-4120948-A | Two phase antiperspirant compositions | THE PROCTER & GAMBLE COMPANY (US) | 1978-10-17 | — | — | US | claimed |
| US-4055659-A | Retinoic acid derivatives | JOHNSON & JOHNSON (US) | 1977-10-25 | — | — | US | claimed |