Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL17685705 | 1.00 | ALDH1A1 (0.73) | — | |
| Acrylamide SCHEMBL514219 | 1.00 | ALDH1A1 (0.73) | — | |
| Acrylamide SCHEMBL9394608 | 0.97 | ALDH1A1 (0.69) | — | |
| Acrylamide SCHEMBL7752342 | 0.89 | — | — | |
| Acrylamide SCHEMBL28271793 | 0.89 | TSHR (0.58) | — | |
| Acrylamide SCHEMBL28277051 | 0.88 | — | — | |
| Succinic Acid SCHEMBL29045660 | 0.87 | TSHR (0.55) | — | |
| Acrylamide SCHEMBL170034 | 0.86 | TSHR (1.00) | — | |
| Acrylamide SCHEMBL1332245 | 0.86 | — | — | |
| Acrylamide SCHEMBL183292 | 0.86 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117487070-A | Synthesis method of active printing urea substitute polyalkylpolysaccharide compound | 苏州联胜化学有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-113089345-B | Amphoteric polyamine high-molecular polymerization viscose cotton blending leveling agent and preparation method thereof | 苏州联胜化学有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-109289813-A | The adsorbent material of nitrous oxide, preparation method and applications in a kind of Wheat Growing Soils | 长安大学 | 2019-02-01 | — | — | CN | claimed |
| US-20240183076-A1 | HIGH THROUGHOUT SCREENING IN DROPLETS | NOVARTIS AG (CH) | 2024-06-06 | — | — | US | disclosed |
| CN-111629746-B | Charge switchable polymer depot for glucose-triggered insulin delivery with ultra-fast response | 北卡罗来纳州立大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-114163659-B | Three-dimensional dynamic self-repairing photonic crystal hydrogel based on cyclodextrin inclusion effect and construction method thereof | 江苏大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117487070-A | Synthesis method of active printing urea substitute polyalkylpolysaccharide compound | 苏州联胜化学有限公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-4304769-A1 | HIGH THROUGHOUT SCREENING IN DROPLETS | Novartis AG (CH) | 2024-01-17 | — | — | EP | disclosed |
| CN-116940408-A | High throughput screening in droplets | 诺华股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-115012234-B | Deflocculating leveling agent for reactive dyeing of reuse water and preparation method thereof | 苏州联胜化学有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-113089345-B | Amphoteric polyamine high-molecular polymerization viscose cotton blending leveling agent and preparation method thereof | 苏州联胜化学有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-106832158-B | PH-responsive dynamic shell cross-linked polymer nano-particle and preparation method thereof | 湖南工业大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-111629746-A | Charge switchable polymer depot for glucose triggered insulin delivery with ultra-fast response | 北卡罗来纳州立大学 | 2020-09-04 | — | — | CN | disclosed |
| CN-109289813-A | The adsorbent material of nitrous oxide, preparation method and applications in a kind of Wheat Growing Soils | 长安大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-109289813-A | The adsorbent material of nitrous oxide, preparation method and applications in a kind of Wheat Growing Soils | 长安大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-104109518-B | Displacement composition for low-permeability oil deposit and preparation method thereof | 中国石油化工股份有限公司 | 2018-02-13 | — | — | CN | disclosed |
| EP-1669398-B1 | FLAME-RETARDANT PROCESSED RESIN OBTAINED WITH A REACTIVE FLAME RETARDANT | FUJI ELECTRIC CO LTD (JP) | 2014-01-08 | — | — | EP | disclosed |
| CN-101817755-B | 4-chlorobutyl-trimethyl-ammonium halide and preparation method thereof | UNIV CHINA GEOSCIENCES WUHAN | 2013-04-03 | — | — | CN | disclosed |
| EP-1669398-A1 | REACTIVE FLAME RETARDANT AND FLAME-RETARDANT PROCESSED RESIN OBTAINED WITH THE SAME | FUJI ELECTRIC HOLDINGS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |