Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706106 | 0.80 | — | — | |
| SCHEMBL9491619 | 0.80 | — | — | |
| SCHEMBL18414215 | 0.80 | — | — | |
| Butadiene Epoxide SCHEMBL6067380 | 0.75 | TDP1 (0.56) | TDP1 | |
| SCHEMBL13392813 | 0.73 | TDP1 (0.36) | TDP1 | |
| SCHEMBL10419855 | 0.70 | EPHX1 (0.31) | — | |
| Butadiene Epoxide SCHEMBL39877 | 0.68 | — | — | |
| Butadiene Epoxide SCHEMBL335040 | 0.68 | — | — | |
| SCHEMBL7637416 | 0.67 | ALDH1A1 (0.42) | — | |
| Butadiene Epoxide SCHEMBL10496505 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682555-A1 | MACROCYCLIC KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005047294-A1 | MACROCYCLIC KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2005-05-26 | — | — | WO | disclosed |