Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9603471 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EDPP4TSHR | |
| SCHEMBL19032451 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EDPP4TSHR | |
| SCHEMBL8398744 | 0.81 | KDM4E (0.37) | ALDH1A1KDM4ETLR8TLR7NPSR1 | |
| SCHEMBL8121341 | 0.79 | — | — | |
| SCHEMBL7446808 | 0.78 | CARM1 (0.56) | CARM1PRMT6PRMT8KMT2AALDH1A1 | |
| SCHEMBL15767946 | 0.77 | CARM1 (0.37) | CARM1PRMT6PRMT8LMNAMEN1 | |
| SCHEMBL15768040 | 0.77 | CARM1 (0.37) | CARM1PRMT6PRMT8LMNAMEN1 | |
| SCHEMBL12302972 | 0.76 | CARM1 (0.54) | CARM1PRMT6PRMT8ALDH1A1KDM4E | |
| SCHEMBL26442095 | 0.76 | SLC2A1 (0.35) | — | |
| SCHEMBL6739265 | 0.75 | CARM1 (0.46) | CARM1PRMT6PRMT8LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006009143-A1 | PROCESS FOR PRODUCTION OF (3S)-3-HYDROXYMETHYL-7-OXO- PYRIDOBENZOXAZINE-6-CARBOXYLIC ESTERS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-01-26 | — | — | WO | disclosed |