Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548138 | 0.82 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL30507661 | 0.72 | KDM4E (0.46) | ADORA2AADORA1ADORA2BADORA3KDM4E | |
| SCHEMBL7152951 | 0.71 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5653322 | 0.69 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL13979684 | 0.68 | ADORA2A (0.43) | ADORA2AADORA1ADORA2BADORA3KDM4E | |
| SCHEMBL6047213 | 0.68 | ADORA2A (0.82) | ADORA2A | |
| SCHEMBL9429556 | 0.67 | RAB9A (0.46) | ADORA2AADORA1KDM4EALDH1A1TDP1 | |
| SCHEMBL6047267 | 0.67 | ADORA2A (0.74) | ADORA2A | |
| SCHEMBL30153455 | 0.67 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BADORA3KDM4E | |
| SCHEMBL6047223 | 0.67 | ADORA2A (0.64) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633756-A2 | A2A ADENOSINE RECEPTOR ANTAGONISTS | Biogen Idec MA Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004092173-A2 | A2A ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN IDEC MA INC. (US) | 2004-10-28 | — | — | WO | disclosed |