SCHEMBL6006923

SCHEMBL6006923

NC(C(=O)O)C(N)S(=O)(=O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 3/20 0.66
SLC1A2 P43004 3/20 0.66
NPSR1 Q6W5P4 2/20 0.53
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
MMP1 P03956 1/20 0.51
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51
MMP8 P22894 1/20 0.51
MMP13 P45452 1/20 0.51
GAA P10253 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SLC1A1 P43005 2/20 0.47
CES2 O00748 2/20 0.46
KAT6A Q92794 1/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
POLB P06746 1/20 0.45
MMP7 P09237 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6006917 1.00 SLC1A3 (0.66) SLC1A3SLC1A2NPSR1CA1CA2
SCHEMBL8619633 0.83 SLC1A2 (0.61) SLC1A3SLC1A2CA1CA2MMP1
SCHEMBL7651611 0.79 SLC1A2 (0.54) SLC1A3SLC1A2CA1CA2GAA
SCHEMBL382144 0.79 SLC1A2 (0.54) SLC1A3SLC1A2CA1CA2GAA
SCHEMBL6009004 0.79 SLC1A3 (0.46) SLC1A3SLC1A2KMT2ASLC1A1KAT6A
SCHEMBL6009009 0.79 SLC1A3 (0.46) SLC1A3SLC1A2KMT2ASLC1A1KAT6A
Hydrochloric Acid SCHEMBL7373021 0.78 SLC1A3 (0.44) SLC1A3SLC1A2KMT2ASLC1A1KAT6A
Hydrochloric Acid SCHEMBL382914 0.77 SLC1A2 (0.53) SLC1A3SLC1A2CA1CA2GAA
SCHEMBL7870776 0.77 SLC1A3 (0.56) SLC1A3SLC1A2NPSR1CA1CA2
SCHEMBL2629467 0.74 CA1 (0.56) SLC1A3SLC1A2NPSR1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0832076-A1 NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-04-01 EP claimed
WO-1996038426-A1 NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-12-05 WO claimed
EP-0920345-A4 IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS VYTERIS INC (US) 2006-05-10 EP disclosed
EP-0920345-A1 IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS Becton Dickinson and Company (US) 1999-06-09 EP disclosed
WO-1997048443-A1 IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS BECTON DICKINSON AND COMPANY (US) 1997-12-24 WO disclosed