Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 4/20 | 0.61 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.61 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.61 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6006917 | 0.83 | SLC1A3 (0.66) | SLC1A2SLC1A3SLC1A1MMP1MMP2 | |
| SCHEMBL6006923 | 0.83 | SLC1A3 (0.66) | SLC1A2SLC1A3SLC1A1MMP1MMP2 | |
| SCHEMBL7651611 | 0.79 | SLC1A2 (0.54) | SLC1A2SLC1A3SLC1A1CA12CA1 | |
| SCHEMBL382144 | 0.79 | SLC1A2 (0.54) | SLC1A2SLC1A3SLC1A1CA12CA1 | |
| SCHEMBL7372101 | 0.78 | SLC1A3 (0.58) | SLC1A2SLC1A3SLC1A1MMP1MMP2 | |
| SCHEMBL9094528 | 0.78 | SLC1A3 (0.58) | SLC1A2SLC1A3SLC1A1MMP1MMP2 | |
| SCHEMBL8861438 | 0.78 | SLC1A2 (0.41) | SLC1A2SLC1A3SLC1A1MMP1MMP2 | |
| SCHEMBL8861442 | 0.78 | SLC1A2 (0.41) | SLC1A2SLC1A3SLC1A1MMP1MMP2 | |
| Hydrochloric Acid SCHEMBL382914 | 0.78 | SLC1A2 (0.53) | SLC1A2SLC1A3SLC1A1CA12CA1 | |
| SCHEMBL8949440 | 0.77 | SLC1A3 (0.49) | SLC1A2SLC1A3SLC1A1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996038426-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-05 | — | — | WO | claimed |