Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19862096 | 0.86 | MAOA (0.47) | RAD51KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL4748830 | 0.85 | MAPT (0.55) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL908398 | 0.82 | MEN1 (0.52) | RAD51S1PR2KDM4EMAPTMEN1 | |
| SCHEMBL25068057 | 0.81 | KDM4E (0.58) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL602093 | 0.81 | KDM4E (0.61) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL20222411 | 0.81 | MEN1 (0.55) | RAD51KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL8321136 | 0.81 | RAD51 (0.43) | RAD51KDM4EALDH1A1HPGDADORA3 | |
| SCHEMBL4716132 | 0.81 | RAD51 (0.48) | RAD51KDM4EALDH1A1ADORA3CXCL12 | |
| SCHEMBL604498 | 0.81 | PFKFB3 (0.46) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL10685624 | 0.79 | GSK3B (0.46) | KDM4EMAPTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102428082-A | Pyrimidine compounds and their use in pest control | SUMITOMO CHEMICAL CO | 2012-04-25 | — | — | CN | disclosed |
| EP-2432780-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| WO-2010134478-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | WO | disclosed |
| US-7091206-B2 | Process for producing pyrimidine derivative and intermediate thereof | NIPPON SHINYAKU CO., LTD (JP) | 2006-08-15 | — | — | US | disclosed |
| US-7091206-B2 | Process for producing pyrimidine derivative and intermediate thereof | NIPPON SHINYAKU CO., LTD (JP) | 2006-08-15 | — | — | US | disclosed |
| EP-1318146-B1 | PROCESS FOR PRODUCING PYRIMIDINE DERIVATIVE AND INTERMEDIATE THEREOF | NIPPON SHINYAKU CO LTD (JP) | 2005-02-23 | — | — | EP | disclosed |
| EP-1318146-B1 | PROCESS FOR PRODUCING PYRIMIDINE DERIVATIVE AND INTERMEDIATE THEREOF | NIPPON SHINYAKU CO LTD (JP) | 2005-02-23 | — | — | EP | disclosed |
| EP-0781766-B1 | HETEROCYCLIC DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-20040023985-A1 | Process for producing pyrimidine derivative and intermediate thereof | NIPPON SHINYAKU CO., LTD. (JP) | 2004-02-05 | — | — | US | disclosed |
| US-20040023985-A1 | Process for producing pyrimidine derivative and intermediate thereof | NIPPON SHINYAKU CO., LTD. (JP) | 2004-02-05 | — | — | US | disclosed |
| CN-1118454-C | Heterocyclic derivative and medicine | NIPPON SHINYAKU CO LTD (JP) | 2003-08-20 | — | — | CN | disclosed |
| EP-1318146-A1 | PROCESS FOR PRODUCING PYRIMIDINE DERIVATIVE AND INTERMEDIATE THEREOF | Nippon Shinyaku Co., Ltd. (JP) | 2003-06-11 | — | — | EP | disclosed |
| EP-1318146-A1 | PROCESS FOR PRODUCING PYRIMIDINE DERIVATIVE AND INTERMEDIATE THEREOF | Nippon Shinyaku Co., Ltd. (JP) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020494-A1 | PROCESS FOR PRODUCING PYRIMIDINE DERIVATIVE AND INTERMEDIATE THEREOF | NIPPON SHINYAKU CO., LTD. (JP) | 2002-03-14 | — | — | WO | disclosed |
| US-6191149-B1 | DRUG FOR CEREBROVASCULAR DISEASE | NIPPON SHINYAKU, CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| US-5945426-A | PREVENT NEURONAL DEATH | NIPPON SHINYAKU CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0781766-A1 | HETEROCYCLIC DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1997-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | TYMP, DPYD, TYMS | RAD51 1025/4885S1PR2 794/4885KDM4E 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.