SCHEMBL19862096

SCHEMBL19862096

Cc1nc(-c2ccc(F)cc2)cc(-c2ccc(F)cc2)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
RAD51 Q06609 1/20 0.46
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
NPSR1 Q6W5P4 4/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
ADORA2A P29274 1/20 0.45
PFKFB3 Q16875 1/20 0.45
RAB9A P51151 4/20 0.44
ALOX5 P09917 1/20 0.44
MGAM O43451 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20222411 0.94 MEN1 (0.55) MAOAMAOBRAD51KDM4EALDH1A1
SCHEMBL8321136 0.90 RAD51 (0.43) MAOAMAOBRAD51KDM4EALDH1A1
SCHEMBL5420904 0.86 ADORA3 (0.43) RAD51KDM4EALDH1A1L3MBTL1HPGD
SCHEMBL600729 0.86 RAD51 (0.44) RAD51KDM4EALDH1A1L3MBTL1MAPT
SCHEMBL12202948 0.83 ADORA3 (0.41) MAOAMAOBRAD51KDM4EALDH1A1
SCHEMBL603770 0.82 KDM4E (0.51) MAOAMAOBKDM4EALDH1A1L3MBTL1
SCHEMBL12264966 0.81 MAPT (0.59) MAOAMAOBKDM4EALDH1A1L3MBTL1
SCHEMBL17679134 0.79 L3MBTL1 (0.64) KDM4EALDH1A1L3MBTL1MAPTHPGD
SCHEMBL601256 0.78 RAD51 (0.45) MAOAMAOBRAD51KDM4EALDH1A1
SCHEMBL5592818 0.78 MEN1 (0.51) RAD51KDM4EALDH1A1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME ORC3, AOX1, RCOR3 MAOA 1867/4885MAOB 1020/4885RAD51 2183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.