SCHEMBL6007913

SCHEMBL6007913

CNCC(Cc1ccc(Cl)c(Cl)c1)N1CCC(Cc2ccccc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 2/20 0.49
PRMT6 Q96LA8 2/20 0.49
ALDH1A1 P00352 3/20 0.44
ATM Q13315 2/20 0.44
CCR3 P51677 1/20 0.42
NPFFR1 Q9GZQ6 1/20 0.42
NPFFR2 Q9Y5X5 1/20 0.42
HRH3 Q9Y5N1 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5792327 0.86 ALDH1A1 (0.42) ALDH1A1ATMCCR3NPFFR1NPFFR2
Hydrochloric Acid SCHEMBL5758292 0.84 ALDH1A1 (0.46) CARM1PRMT6ALDH1A1ATMCCR3
Benzylamine SCHEMBL5824111 0.83 ALDH1A1 (0.43) CARM1PRMT6ALDH1A1ATMCCR3
SCHEMBL6206654 0.81 CARM1 (0.50) CARM1PRMT6SIGMAR1
SCHEMBL6007980 0.78 CARM1 (0.52) CARM1PRMT6ALDH1A1ATMCCR3
SCHEMBL6009428 0.74 ALDH1A1 (0.53) CARM1PRMT6ALDH1A1ATMCCR3
Hydrochloric Acid SCHEMBL6007421 0.73 ALDH1A1 (0.52) CARM1PRMT6ALDH1A1ATMCCR3
SCHEMBL27014972 0.73 HRH3 (0.50) CCR3HRH3SIGMAR1
SCHEMBL6007453 0.72 ALDH1A1 (0.49) CARM1PRMT6ALDH1A1ATMCCR3
Hydrochloric Acid SCHEMBL8905427 0.72 CARM1 (0.53) CARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078537-B2 Phenylalkyl diamine and amide analogs SK CORPORATION (KR) 2006-07-18 US disclosed
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SK BIOPHARMACEUTICALS CO., LTD. (KR) 2003-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SIGMAR1, TAAR1, OPRL1 CARM1 4111/4885PRMT6 1600/4885ALDH1A1 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.