Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007978 | 1.00 | GRM2 (0.47) | GRM2HSD11B1HTR2AMEN1KMT2A | |
| SCHEMBL4487651 | 0.85 | S1PR1 (0.47) | HSD11B1MEN1KMT2AARG1ARG2 | |
| SCHEMBL3259925 | 0.85 | S1PR1 (0.47) | HSD11B1MEN1KMT2AARG1ARG2 | |
| SCHEMBL3228487 | 0.85 | S1PR1 (0.47) | HSD11B1MEN1KMT2AARG1ARG2 | |
| Hydrochloric Acid SCHEMBL15312500 | 0.84 | BCHE (0.46) | HSD11B1MEN1KMT2AARG1ARG2 | |
| SCHEMBL4673419 | 0.74 | KCNA3 (0.48) | MEN1KMT2AOPRM1 | |
| SCHEMBL4673416 | 0.74 | KCNA3 (0.48) | MEN1KMT2AOPRM1 | |
| SCHEMBL11461429 | 0.74 | SLC6A3 (0.45) | KCNH2SIGMAR1SLC6A3ACHE | |
| SCHEMBL27671990 | 0.73 | SLC6A3 (0.52) | GRM2HSD11B1HTR2AMEN1KMT2A | |
| SCHEMBL7510207 | 0.72 | SLC6A3 (0.44) | GRM2SIGMAR1SLC6A3GBA1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924213-B1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2006-06-28 | — | — | EP | disclosed |
| EP-0807630-B1 | HETEROCYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6191129-B1 | MICROBIOCIDES, BACTERICIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0924213-A1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |