Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988127 | 0.85 | SIGMAR1 (0.43) | SIGMAR1ACHEDRD2 | |
| SCHEMBL9839788 | 0.82 | FUCA1 (0.41) | SIGMAR1ACHEDRD2 | |
| Lithium Ion SCHEMBL9839786 | 0.81 | FUCA1 (0.40) | SIGMAR1ACHEDRD2 | |
| SCHEMBL11461429 | 0.75 | SLC6A3 (0.45) | SLC6A3SIGMAR1ACHEDRD2 | |
| SCHEMBL6007699 | 0.73 | SMN1; SMN2 (0.46) | SLC6A3SIGMAR1ACHECCR3DRD2 | |
| Hydrochloric Acid SCHEMBL11087688 | 0.73 | SLC6A3 (0.44) | SLC6A3SIGMAR1ACHEDRD2 | |
| SCHEMBL6007693 | 0.73 | SMN1; SMN2 (0.46) | SLC6A3SIGMAR1ACHECCR3DRD2 | |
| SCHEMBL22249168 | 0.73 | ROCK2 (0.39) | — | |
| SCHEMBL22248433 | 0.73 | ROCK2 (0.42) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL6007978 | 0.72 | GRM2 (0.47) | SLC6A3SIGMAR1ACHEGBA1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |