Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475007 | 1.00 | VCAM1 (0.48) | VCAM1HSD11B1GAAMAPTTET2 | |
| SCHEMBL249875 | 1.00 | VCAM1 (0.48) | VCAM1HSD11B1GAAMAPTTET2 | |
| SCHEMBL7623197 | 1.00 | VCAM1 (0.48) | VCAM1HSD11B1GAAMAPTTET2 | |
| SCHEMBL3097348 | 0.98 | VCAM1 (0.47) | VCAM1HSD11B1GAAMAPTTET2 | |
| SCHEMBL4581128 | 0.98 | VCAM1 (0.47) | VCAM1HSD11B1GAAMAPTTET2 | |
| SCHEMBL25203443 | 0.98 | VCAM1 (0.47) | VCAM1HSD11B1GAAMAPTTET2 | |
| SCHEMBL28707093 | 0.98 | VCAM1 (0.47) | VCAM1HSD11B1GAAMAPTTET2 | |
| SCHEMBL19021731 | 0.94 | VCAM1 (0.44) | VCAM1HSD11B1GAAMAPTTET2 | |
| SCHEMBL31556895 | 0.93 | HSD11B1 (0.46) | VCAM1HSD11B1MAPTHTR2CHTR2A | |
| SCHEMBL247750 | 0.93 | HSD11B1 (0.46) | VCAM1HSD11B1MAPTHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066569-A2 | IONOMERS AND IONOMER BLENDS BASED ON PARTIALLY FLUORINATED POLY(HETERO)ARYLS | HÄRING, Thomas (DE) | 2006-06-29 | — | — | WO | disclosed |