SCHEMBL6008029

SCHEMBL6008029

O=C(NC(CCN1CCC(Cc2ccccc2)CC1)c1ccccc1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 1/20 0.60
UTS2R Q9UKP6 2/20 0.59
SLC6A2 P23975 4/20 0.58
SLC6A3 Q01959 2/20 0.58
CCR5 P51681 3/20 0.58
SLC6A4 P31645 2/20 0.56
ROCK2 O75116 1/20 0.56
ROCK1 Q13464 1/20 0.56
GRIN2D O15399 1/20 0.55
GRIN3B O60391 1/20 0.55
ADRA1D P25100 1/20 0.55
ADRA1A P35348 1/20 0.55
ADRA1B P35368 1/20 0.55
GRIN1 Q05586 1/20 0.55
GRIN2A Q12879 1/20 0.55
GRIN2B Q13224 1/20 0.55
GRIN2C Q14957 1/20 0.55
GRIN3A Q8TCU5 1/20 0.55
MCHR1 Q99705 1/20 0.55
F2 P00734 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6007211 0.87 SLC6A2 (0.60) CCR3SLC6A2SLC6A3CCR5GRIN2D
SCHEMBL6008823 0.84 UTS2R (0.61) UTS2RCCR5ROCK2ROCK1F2
Hydrochloric Acid SCHEMBL29583409 0.81 UTS2R (0.82) UTS2RCCR5ROCK2ROCK1
SCHEMBL6008830 0.81 PRMT6 (0.63) CCR3SLC6A2SLC6A3GRIN2DGRIN3B
SCHEMBL6333237 0.80 CCR3 (0.61) CCR3SLC6A2SLC6A3CCR5
SCHEMBL6007244 0.80 SLC6A2 (0.56) CCR3SLC6A2SLC6A3GRIN2DGRIN3B
SCHEMBL6338952 0.79 EPHX2 (0.55) CCR3SLC6A2SLC6A3GRIN2DGRIN3B
SCHEMBL6009258 0.79 SIGMAR1 (0.54) SLC6A2SLC6A3CCR5SLC6A4GRIN2D
SCHEMBL6008053 0.78 SLC6A2 (0.54) CCR3SLC6A2SLC6A3CCR5GRIN2D
SCHEMBL6215029 0.78 GRIN2B (0.85) CCR3SLC6A2SLC6A3SLC6A4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078537-B2 Phenylalkyl diamine and amide analogs SK CORPORATION (KR) 2006-07-18 US claimed
US-7078537-B2 Phenylalkyl diamine and amide analogs SK CORPORATION (KR) 2006-07-18 US disclosed
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SK BIOPHARMACEUTICALS CO., LTD. (KR) 2003-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SIGMAR1, TAAR1, OPRL1 CCR3 799/4885UTS2R 492/4885SLC6A2 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.