Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12878375 | 0.86 | ADAM17 (0.44) | ADAM17TNF | |
| SCHEMBL10112013 | 0.84 | ADAM17 (0.43) | ADAM17TNF | |
| SCHEMBL10112103 | 0.84 | ADAM17 (0.43) | ADAM17TNF | |
| SCHEMBL10112111 | 0.79 | ADAM17 (0.44) | ADAM17TNF | |
| SCHEMBL13218722 | 0.78 | ADAM17 (0.38) | ADAM17TNF | |
| SCHEMBL6008382 | 0.77 | ADAM17 (0.44) | ADAM17TNF | |
| SCHEMBL12862659 | 0.76 | ADAM17 (0.43) | ADAM17TNF | |
| SCHEMBL10263491 | 0.76 | ADAM17 (0.41) | ADAM17TNF | |
| SCHEMBL13201492 | 0.76 | DRD2 (0.41) | ADAM17TNF | |
| SCHEMBL17570767 | 0.76 | ADAM17 (0.46) | ADAM17TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488745-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2009-02-10 | — | — | US | disclosed |