Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385431 | 0.88 | CHRM1 (0.37) | CHRM1ALOX15BLMPMP22LMNA | |
| SCHEMBL14615759 | 0.82 | LTA4H (0.32) | ALOX15BLMPMP22LMNALTA4H | |
| SCHEMBL26677535 | 0.80 | KMT2A (0.34) | ALOX15BLMPMP22LTA4HKMT2A | |
| SCHEMBL13804019 | 0.79 | ALDH1A1 (0.47) | CHRM1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7942491 | 0.78 | CHRM1 (0.48) | CHRM1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6402859 | 0.78 | TDP1 (0.39) | — | |
| Octadecanoic Acid Amide SCHEMBL27396491 | 0.78 | SOAT1 (0.52) | ALOX15ALDH1A1KMT2AMEN1FAAH | |
| SCHEMBL440142 | 0.77 | PHF8 (0.44) | CHRM1LMNA | |
| SCHEMBL10906178 | 0.76 | LTA4H (0.33) | ALOX15BLMPMP22LMNALTA4H | |
| SCHEMBL10256965 | 0.76 | KMT2A (0.48) | ALOX15BLMPMP22LMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919443-B1 | STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS AGAINST DEGRADATION BY UV RADIATION USING MEROCYANINE DERIVATIVES | BASF SE (DE) | 2020-06-10 | — | — | EP | disclosed |
| EP-1713781-A1 | QUINAZOLINE DERIVATIVES | AstraZeneca AB (SE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005075439-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |