Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.41 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30534511 | 1.00 | POLB (0.46) | POLBKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL16428885 | 1.00 | POLB (0.46) | POLBKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL251503 | 1.00 | POLB (0.46) | POLBKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL2870793 | 0.98 | POLB (0.44) | POLBKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL124383 | 0.98 | POLB (0.44) | POLBKDM4EALDH1A1CYP3A4MAPK1 | |
| Potassium SCHEMBL7623055 | 0.98 | POLB (0.44) | POLBKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL15030545 | 0.92 | POLB (0.41) | POLBKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL31556894 | 0.92 | ALDH1A1 (0.59) | POLBKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL250259 | 0.92 | ALDH1A1 (0.59) | POLBKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL1878944 | 0.91 | KDM4E (0.50) | POLBKDM4EALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066569-A2 | IONOMERS AND IONOMER BLENDS BASED ON PARTIALLY FLUORINATED POLY(HETERO)ARYLS | HÄRING, Thomas (DE) | 2006-06-29 | — | — | WO | disclosed |