Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16428885 | 0.98 | POLB (0.46) | POLBKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL251503 | 0.98 | POLB (0.46) | POLBKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL6008968 | 0.98 | POLB (0.46) | POLBKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL30534511 | 0.98 | POLB (0.46) | POLBKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL2870793 | 0.96 | POLB (0.44) | POLBKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL124383 | 0.96 | POLB (0.44) | POLBKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL15030545 | 0.90 | POLB (0.41) | POLBKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL31556894 | 0.90 | ALDH1A1 (0.59) | POLBKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL250259 | 0.90 | ALDH1A1 (0.59) | POLBKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL1878944 | 0.89 | KDM4E (0.50) | POLBKDM4EALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451921-B2 | Block copolymers with sulfonated polyether sulfone units | MEMBRANA GMBH (DE) | 2002-09-17 | — | — | US | disclosed |
| US-20010021764-A1 | Block copolymers with sulfonated polyether sulfone units | MEMBRANA GMBH (DE) | 2001-09-13 | — | — | US | disclosed |