Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.52 |
| ▸ | TOP2A | P11388 | 3/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.48 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009397 | 0.84 | AADAT (0.69) | TOP2ATOP2BAADATPOLBKCNH2 | |
| SCHEMBL6204362 | 0.83 | GSK3B (0.51) | GSK3BTOP2ATOP2BAADATPOLB | |
| SCHEMBL6204357 | 0.83 | GSK3B (0.51) | GSK3BTOP2ATOP2BAADATPOLB | |
| SCHEMBL6635916 | 0.83 | GSK3B (0.49) | GSK3BTOP2ATOP2BAADATPOLB | |
| SCHEMBL10684313 | 0.82 | KDM4E (0.68) | GSK3BTOP2ATOP2BAADATPOLB | |
| SCHEMBL29391130 | 0.82 | KDM4E (0.68) | GSK3BTOP2ATOP2BAADATPOLB | |
| SCHEMBL9740225 | 0.82 | GSK3B (0.56) | GSK3BTOP2ATOP2BAADATPOLB | |
| Hydrochloric Acid SCHEMBL29409478 | 0.81 | KDM4E (0.67) | GSK3BTOP2ATOP2BAADATPOLB | |
| Hydrochloric Acid SCHEMBL8684414 | 0.81 | GSK3B (0.55) | GSK3BTOP2ATOP2BAADATPOLB | |
| SCHEMBL6973262 | 0.81 | CACNA1F (0.53) | GSK3BTOP2ATOP2BPOLBCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924213-B1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2006-06-28 | — | — | EP | disclosed |
| US-6191129-B1 | MICROBIOCIDES, BACTERICIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0924213-A1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |