SCHEMBL6009050

SCHEMBL6009050

CCc1cccc2[nH]c3cccc(CC)c3c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.54
MEN1 O00255 1/20 0.54
POLB P06746 1/20 0.54
KMT2A Q03164 1/20 0.54
GABRA1 P14867 3/20 0.46
GABRB2 P47870 3/20 0.46
DAO P14920 3/20 0.46
DDO Q99489 1/20 0.46
PLA2G2A P14555 1/20 0.44
BCHE P06276 2/20 0.43
ACHE P22303 2/20 0.43
CDK1 P06493 1/20 0.42
CDK2 P24941 1/20 0.42
NPEPPS P55786 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
KIF11 P52732 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6007824 0.90 MEN1 (0.48) MAPTMEN1POLBKMT2AGABRA1
SCHEMBL6007652 0.86 BCHE (0.61) MAPTMEN1POLBKMT2AGABRA1
SCHEMBL6008274 0.82 BCHE (0.43) MAPTMEN1POLBKMT2ADAO
SCHEMBL28220277 0.81 ABCG2 (0.59) MAPTMEN1POLBKMT2ADAO
SCHEMBL7030747 0.80 DAO (0.46) MAPTMEN1POLBKMT2AGABRA1
SCHEMBL27844290 0.78 MEN1 (0.63) MAPTMEN1POLBKMT2ADAO
SCHEMBL4509421 0.77 F2 (0.49) MAPTMEN1POLBKMT2AGABRA1
SCHEMBL11292985 0.76 MEN1 (0.40) MAPTMEN1POLBKMT2AGABRA1
SCHEMBL9085281 0.76 PLA2G2A (0.42) MAPTMEN1POLBKMT2AGABRA1
SCHEMBL4734469 0.76 MAPT (0.40) MAPTMEN1POLBKMT2AGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060183022-A1 Electrochemical cell NEC TOKIN CORORATION (JP) 2006-08-17 US disclosed