Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7486372 | 0.99 | ABCB1 (0.51) | ABCB1TSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL5698929 | 0.82 | ABCB1 (0.57) | ABCB1TSHRHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL15445664 | 0.80 | TSHR (0.72) | ABCB1TSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8206119 | 0.80 | ATM (0.48) | ABCB1TSHRALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3072574 | 0.79 | LMNA (0.48) | ABCB1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7534159 | 0.77 | KDM4E (0.62) | ABCB1TSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL7523557 | 0.75 | POLB (0.55) | ABCB1TSHRHSD17B10ALDH1A1KDM4E | |
| Bgp-15 SCHEMBL2325445 | 0.74 | ABCB1 (0.46) | ABCB1TSHRKDM4ESMN1; SMN2CYP2D6 | |
| Bgp-15 SCHEMBL29358886 | 0.74 | ABCB1 (0.46) | ABCB1TSHRKDM4ESMN1; SMN2CYP2D6 | |
| SCHEMBL8610389 | 0.74 | KDM4E (0.57) | ABCB1TSHRHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148239-B2 | Method of enhancing cellular production of molecular chaperon, hydroxylamine derivatives useful for enhancing the chaperon production and the preparation thereof | CYTRX CORPORATION (US) | 2006-12-12 | — | — | US | disclosed |