Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610389 | 0.96 | KDM4E (0.57) | KDM4EPOLBALDH1A1MAPTALOX15 | |
| SCHEMBL7523557 | 0.87 | POLB (0.55) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL15445664 | 0.80 | TSHR (0.72) | KDM4EPOLBALDH1A1MAPTALOX15 | |
| SCHEMBL8610392 | 0.79 | POLB (0.56) | KDM4EPOLBALDH1A1MAPTALOX15 | |
| SCHEMBL3175907 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2AABCB1 | |
| SCHEMBL7559747 | 0.79 | PRMT5 (0.46) | KDM4EPOLBABCB1ATMCYP2D6 | |
| SCHEMBL6009221 | 0.77 | ABCB1 (0.52) | KDM4EPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL7526130 | 0.77 | ABCB1 (0.49) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7486372 | 0.76 | ABCB1 (0.51) | KDM4EPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL7525705 | 0.76 | HRH3 (0.52) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832079-B1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO FEJLESZTOE KFT (HU) | 2002-03-27 | — | — | EP | disclosed |
| US-6002002-A | Anti-ischaemic hydroxylamine derivatives and pharmaceutical compositions | BIOREX RESEARCH & DEVELOPMENT CO. (HU) | 1999-12-14 | — | — | US | disclosed |