Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009973 | 0.80 | GRIN2B (0.53) | GRIN2BTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5510014 | 0.80 | MAOA (0.47) | GRIN2BTP53CYP1A2CYP3A4TSHR | |
| SCHEMBL5504382 | 0.75 | KDM4E (0.35) | GRIN2BKDM4E | |
| SCHEMBL5510564 | 0.74 | GRIN2B (0.48) | GRIN2BTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9536408 | 0.73 | TP53 (0.67) | GRIN2BTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5504911 | 0.73 | KDM4E (0.46) | GRIN2BCYP1A2CYP2D6KMT2AKDM4E | |
| SCHEMBL9536401 | 0.72 | PRMT5 (0.59) | GRIN2BTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17560270 | 0.71 | PRMT5 (0.58) | GRIN2BTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14500131 | 0.71 | GRIN2B (0.57) | GRIN2BTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6009887 | 0.71 | KDM4E (0.48) | CYP1A2CYP2D6KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | APP, PSEN1, TTR | GRIN2B 2271/4885TP53 413/4885CYP1A2 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.