SCHEMBL6009579

SCHEMBL6009579

CS(=O)(O)(O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.35
CA4 P22748 3/20 0.35
CES2 O00748 4/20 0.33
CES1 P23141 4/20 0.33
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
NAPRT Q6XQN6 2/20 0.33
DAO P14920 1/20 0.33
IDO1 P14902 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
GLA P06280 1/20 0.32
CA3 P07451 1/20 0.32
CA9 Q16790 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA14 Q9ULX7 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28958130 0.77 TSHR (0.39) CA2CA4CES2CES1TSHR
SCHEMBL3684648 0.77 TSHR (0.35) CA4CES2CES1TSHRALDH1A1
SCHEMBL10639940 0.77 NPSR1 (0.38) CA2CA4CES2CES1TSHR
SCHEMBL278265 0.77 TSHR (0.39) CA2CA4CES2CES1TSHR
SCHEMBL17963728 0.77 TSHR (0.35) CA4CES2CES1TSHRALDH1A1
SCHEMBL3883735 0.76 TDP1 (0.42) CA2CES2CES1TSHRALDH1A1
SCHEMBL11222508 0.76 CA4 (0.32) CA4TSHRLMNAALOX12ACHE
SCHEMBL776834 0.74 CA1 (0.41) CA2CES2CES1ALDH1A1CA1
SCHEMBL3883834 0.74 ACHE (0.46) TSHRALDH1A1HSD17B10LMNAACHE
SCHEMBL5042529 0.72 CES1 (0.33) CA2CA4CES2CES1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101143192-B Therapeutic gastrodia elata extract ACADEMIA SINICA 2011-04-27 CN disclosed
CN-101524361-A Methods of making and using adenosine analogs ACADEMIA SINICA 2009-09-09 CN disclosed
CN-101143192-A Therapeutic gastrodia elata extract ACADEMIA SINICA (CN) 2008-03-19 CN disclosed
EP-1148570-B1 Nonaqueous electrolyte secondary battery SONY CORP (JP) 2006-06-07 EP disclosed
US-20050208385-A1 Negative electrode active material capable of being doped/undoped with lithium, and a nonaqueous electrolyte of thiols, thiophenes, thioanisoles, thiazoles, thioacetates, aromatic sulfones; longer cycle life NIRASAWA TAKAO 2005-09-22 US disclosed
US-6913856-B2 Sulfur compound as nonaqueous electrolyte SONY CORPORATION (JP) 2005-07-05 US disclosed
US-20020018940-A1 Sulfur compound as nonaqueous electrolyte SONY CORPORATION (JP) 2002-02-14 US disclosed
EP-1148570-A2 Nonaqueous electrolyte secondary battery SONY CORPORATION (JP) 2001-10-24 EP disclosed