SCHEMBL3684648

SCHEMBL3684648

CS(C)(C)(=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35
ACHE P22303 1/20 0.35
ALDH1A1 P00352 5/20 0.33
CTSD P07339 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
BBOX1 O75936 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
CES2 O00748 2/20 0.31
CES1 P23141 2/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
PSIP1 O75475 1/20 0.31
DAO P14920 1/20 0.30
NAPRT Q6XQN6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17963728 0.81 TSHR (0.35) TSHRLMNAALOX12ACHEALDH1A1
SCHEMBL17400778 0.77 LMNA (0.32) TSHRLMNAALOX12ACHEBBOX1
SCHEMBL11222508 0.75 CA4 (0.32) TSHRLMNAALOX12ACHECA4
SCHEMBL25006070 0.73 TAAR1 (0.34) LMNAALDH1A1TDP1KMT2ACYP2A6
SCHEMBL11286036 0.73 CA4 (0.36) TSHRLMNAALDH1A1TDP1CYP3A4
SCHEMBL11283884 0.73 CA4 (0.36) TSHRLMNAALDH1A1TDP1CYP3A4
SCHEMBL13591915 0.69 CYP3A4 (0.48) TSHRLMNAALDH1A1TDP1CYP3A4
SCHEMBL9051640 0.69 TP53 (0.38) TSHRLMNAALOX12ACHEALDH1A1
SCHEMBL11288437 0.69 CA4 (0.38) TSHRLMNAALOX12ACHEALDH1A1
SCHEMBL6003247 0.69 BBOX1 (0.33) TSHRALDH1A1BBOX1EHMT2EHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3099304-B1 CHROMAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF GLAUCOMA MAYO FOUND MEDICAL EDUCATION & RES (US) 2024-07-17 EP disclosed
EP-3489235-A1 TRICYCLIC COMPOUND AS CRTH2 INHIBITOR Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2019-05-29 EP disclosed
EP-1867662-B2 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same IDEMITSU KOSAN CO (JP) 2013-02-27 EP disclosed
US-8357235-B2 Inkjet ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-22 US disclosed
EP-1231236-B1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU KOSAN CO (JP) 2012-12-05 EP disclosed
US-20100242791-A1 INKJET INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
EP-2028198-B1 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containinig the same IDEMITSU KOSAN CO (JP) 2010-01-06 EP disclosed
US-20090215973-A1 PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-08-27 US disclosed
EP-1772467-B1 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same IDEMITSU KOSAN CO (JP) 2009-08-05 EP disclosed
EP-1865006-B1 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same IDEMITSU KOSAN CO (JP) 2009-06-24 EP disclosed
US-20030017940-A1 Transition metal compound, polymerization catalysts for olefin , olefin polymers and process for their production IDEMITSU KOSAN CO. LTD. (JP) 2003-01-23 US disclosed
EP-1247814-A1 TRANSITION METAL COMPOUNDS, POLYMERIZATION CATALYSTS FOR OLEFINS, OLEFIN POLYMERS AND PROCESS FOR THEIR PRODUCTION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-10-09 EP disclosed
EP-1241206-A1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-09-18 EP disclosed
EP-1231226-A1 ROLLED POLYPROPYLENE AND INJECTION-MOLDED POLYPROPYLENE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1231236-A1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1227112-A1 PROPYLENE POLYMERS AND RESIN COMPOSITION AND MOLDING CONTAINING THE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-07-31 EP disclosed
EP-1095951-A1 PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-05-02 EP disclosed
EP-0377743-B1 STEROID COMPOUNDS KURARAY CO (JP) 1995-06-28 EP disclosed
US-5218109-A STEROID COMPOUNDS KURARAY CO., LTD. (JP) 1993-06-08 US disclosed
US-4327100-A USEFUL AS HYPERTENSIVE AND CARDIOTONIC AGENTS BOEHRINGER INGELHEIM GMBH (DE) 1982-04-27 US disclosed