Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31167250 | 1.00 | PARP1 (0.65) | PARP1TP53SMN1; SMN2LMNADAO | |
| SCHEMBL2141394 | 0.95 | PARP1 (0.61) | PARP1TP53SMN1; SMN2LMNADAO | |
| SCHEMBL30659227 | 0.89 | AHR (0.64) | PARP1LMNAHPGDALDH1A1HSD17B10 | |
| SCHEMBL4670015 | 0.89 | AHR (0.64) | PARP1LMNAHPGDALDH1A1HSD17B10 | |
| SCHEMBL6009586 | 0.87 | KIF11 (0.62) | PARP1TP53SMN1; SMN2LMNACA9 | |
| SCHEMBL11532887 | 0.87 | PARP1 (0.53) | PARP1TP53SMN1; SMN2LMNACA9 | |
| SCHEMBL14543827 | 0.85 | PARP1 (0.62) | PARP1TP53SMN1; SMN2LMNADAO | |
| SCHEMBL29371976 | 0.84 | PARP1 (0.50) | PARP1TP53SMN1; SMN2LMNADAO | |
| SCHEMBL20208814 | 0.84 | PARP1 (0.50) | PARP1TP53SMN1; SMN2LMNADAO | |
| SCHEMBL15741317 | 0.83 | PARP1 (0.50) | PARP1TP53SMN1; SMN2LMNADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574429-A | Carbazolyl-containing aromatic polyamine monomer and preparation method and application thereof | 上海华谊树脂有限公司 | 2020-08-25 | — | — | CN | claimed |
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | SHEFFIELD, THE UNIVERSITY OF (GB) | 2005-06-02 | — | — | US | claimed |
| EP-1453802-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2004-09-08 | — | — | EP | claimed |
| WO-2003050086-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2003-06-19 | — | — | WO | claimed |
| CN-111574429-A | Carbazolyl-containing aromatic polyamine monomer and preparation method and application thereof | 上海华谊树脂有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-105237462-A | Diamine monomer containing carbazole structure and having high planarity, synthetic method and application thereof | UNIV HUNAN TECHNOLOGY | 2016-01-13 | — | — | CN | disclosed |
| US-7138483-B2 | Monomers, conjugated polymers and electronic devices using such polymers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-11-21 | — | — | US | disclosed |
| US-20060183022-A1 | Electrochemical cell | NEC TOKIN CORORATION (JP) | 2006-08-17 | — | — | US | disclosed |
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | SHEFFIELD, THE UNIVERSITY OF (GB) | 2005-06-02 | — | — | US | disclosed |
| US-6833432-B2 | Electronics, optics | UNIVERSITE LAVAL (CA) | 2004-12-21 | — | — | US | disclosed |
| US-20040192871-A1 | Monomers, conjugated polymers and electronic devices using such polymers | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| EP-1453802-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2004-09-08 | — | — | EP | disclosed |
| WO-2004072123-A2 | MONOMERS, CONJUGATED POLYMERS AND ELECTRONIC DEVICES USING SUCH POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-08-26 | — | — | WO | disclosed |
| WO-2003050086-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2003-06-19 | — | — | WO | disclosed |
| US-20030092880-A1 | Conjugated poly(2,7-carbazole) derivatives and process for the preparation thereof | UNIVERSITE LAVAL (CA) | 2003-05-15 | — | — | US | disclosed |
| US-20020103332-A1 | Conjugated polycarbazole derivatives and process for the preparation thereof | UNIVERSITE LAVAL (CA) | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | CBR3, OR10J3, ORC3 | PARP1 1165/4885TP53 3504/4885SMN1; SMN2 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.