Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29586144 | 0.96 | PARP1 (0.58) | PARP1SMN1; SMN2TP53LMNACA1 | |
| SCHEMBL14543826 | 0.92 | PARP1 (0.59) | PARP1SMN1; SMN2TP53LMNACA1 | |
| SCHEMBL4231006 | 0.90 | GAA (0.67) | PARP1SMN1; SMN2TP53LMNACA1 | |
| SCHEMBL3609835 | 0.89 | GRIN2D (0.54) | PARP1SMN1; SMN2TP53LMNACA9 | |
| SCHEMBL6009587 | 0.85 | PARP1 (0.65) | PARP1SMN1; SMN2TP53LMNADAO | |
| SCHEMBL31167250 | 0.85 | PARP1 (0.65) | PARP1SMN1; SMN2TP53LMNADAO | |
| SCHEMBL28405063 | 0.84 | ABCG2 (0.56) | PARP1SMN1; SMN2TP53LMNACA9 | |
| SCHEMBL276018 | 0.83 | LMNA (0.56) | PARP1SMN1; SMN2TP53LMNACA1 | |
| SCHEMBL29354683 | 0.83 | LMNA (0.56) | PARP1SMN1; SMN2TP53LMNACA1 | |
| SCHEMBL29586622 | 0.83 | LMNA (0.56) | PARP1SMN1; SMN2TP53LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205311-B2 | Therapeutic acridone and acridine compounds | CANCER RESEARCH TECHNOLOGY LIMITED | 2007-04-17 | — | — | US | disclosed |