Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462063 | 0.83 | TDP1 (0.50) | TDP1L3MBTL1POLBHDAC3HDAC1 | |
| SCHEMBL265617 | 0.81 | TDP1 (0.63) | TDP1L3MBTL1POLBHDAC3HDAC1 | |
| SCHEMBL10449073 | 0.78 | POLB (0.61) | TDP1L3MBTL1POLBHDAC3HDAC1 | |
| SCHEMBL7765596 | 0.78 | TDP1 (0.59) | TDP1L3MBTL1POLBHDAC3HDAC1 | |
| Benzene SCHEMBL28121114 | 0.76 | POLB (0.59) | TDP1L3MBTL1POLBHDAC3HDAC1 | |
| SCHEMBL8173955 | 0.76 | TDP1 (1.00) | TDP1L3MBTL1POLBHDAC3HDAC1 | |
| SCHEMBL9694716 | 0.75 | TDP1 (0.61) | TDP1L3MBTL1POLBHDAC3HDAC1 | |
| SCHEMBL11861445 | 0.75 | TDP1 (0.56) | TDP1L3MBTL1POLBHDAC3HDAC1 | |
| SCHEMBL28850772 | 0.75 | TDP1 (0.56) | TDP1L3MBTL1POLBHDAC3HDAC1 | |
| Ethylene Glycol SCHEMBL28193873 | 0.75 | TDP1 (0.56) | TDP1L3MBTL1POLBHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696898-A2 | ZN 24 -CHELATING MOTIF-TETHERED SHORT-CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-09-06 | — | — | EP | claimed |
| WO-2005055928-A2 | ZN2+ -CHELATING MOTIF-TETHERED SHORT -CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-06-23 | — | — | WO | claimed |