Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10824778 | 0.81 | KMT2A (0.69) | TDP1L3MBTL1HDAC3CA12CA1 | |
| SCHEMBL11369151 | 0.78 | TDP1 (0.59) | TDP1L3MBTL1HDAC3CA12CA1 | |
| SCHEMBL28655712 | 0.78 | TDP1 (0.59) | TDP1L3MBTL1HDAC3CA12CA1 | |
| SCHEMBL9130749 | 0.77 | MTNR1A (0.47) | TDP1L3MBTL1HSD17B10KMT2APOLB | |
| SCHEMBL8173955 | 0.76 | TDP1 (1.00) | TDP1L3MBTL1HDAC3CA12CA1 | |
| SCHEMBL6009689 | 0.75 | TDP1 (0.61) | TDP1L3MBTL1HDAC3CA12CA1 | |
| SCHEMBL7662987 | 0.75 | TDP1 (0.56) | TDP1L3MBTL1HDAC3CA12CA1 | |
| SCHEMBL9134233 | 0.75 | TDP1 (0.56) | TDP1L3MBTL1HDAC1HDAC6KMT2A | |
| SCHEMBL10953024 | 0.75 | TDP1 (0.71) | TDP1L3MBTL1HDAC3CA12CA1 | |
| SCHEMBL7662983 | 0.75 | TDP1 (0.56) | TDP1L3MBTL1HDAC3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089486-A | Fungicides | SHELL RESEARCH LIMITED (GB) | 1992-02-18 | — | — | US | disclosed |
| EP-0411719-A1 | Biocidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-02-06 | — | — | EP | disclosed |