Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14464203 | 0.82 | — | — | |
| SCHEMBL8102869 | 0.78 | LMNA (0.39) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL11520445 | 0.76 | DNM1 (0.44) | KDM4CPHF8LMNAALDH1A1 | |
| SCHEMBL15238200 | 0.70 | KDM4C (0.46) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL28582583 | 0.70 | KDM4C (0.46) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL15563088 | 0.70 | KDM4C (0.42) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL10706945 | 0.70 | KDM4C (0.42) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL8464998 | 0.69 | LMNA (0.48) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL1507494 | 0.69 | LMNA (0.48) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL1507508 | 0.69 | LMNA (0.48) | KDM4CKDM4APHF8KDM2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132441-B2 | Immunosuppressive effects of administration of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor | G.D. SEARLE & CO. (US) | 2006-11-07 | — | — | US | disclosed |
| US-6376528-B1 | SYNERGISTIC MIXTURE | G. D. SEARLE & CO. | 2002-04-23 | — | — | US | disclosed |