Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009058 | 0.84 | CA1 (0.40) | GPR139CA1CA2 | |
| SCHEMBL6008663 | 0.83 | DUT (0.41) | CASRHTR6GPR139KMT2AALDH1A1 | |
| SCHEMBL10278359 | 0.80 | TP53BP1 (0.42) | ADRB1CYP1A2CYP3A4PNMTL3MBTL1 | |
| SCHEMBL10231050 | 0.80 | CYP3A4 (0.53) | SLC6A4DRD3SLC6A2OPRM1CASR | |
| SCHEMBL10231054 | 0.80 | CYP3A4 (0.53) | SLC6A4DRD3SLC6A2OPRM1CASR | |
| SCHEMBL14099965 | 0.80 | CYP3A4 (0.53) | SLC6A4DRD3SLC6A2OPRM1CASR | |
| SCHEMBL353007 | 0.79 | CASR (0.57) | ADRA2CDRD3SLC6A2HTR2COPRM1 | |
| SCHEMBL353006 | 0.79 | CASR (0.57) | ADRA2CDRD3SLC6A2HTR2COPRM1 | |
| SCHEMBL10278322 | 0.78 | TP53BP1 (0.41) | SLC6A4SLC6A2HTTCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10583669 | 0.77 | ADRA2C (0.48) | ADRA2CSLC6A4DRD3SLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | APP, PSEN1, TTR | ADRA2C 480/4885SLC6A4 1538/4885DRD3 3857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.