Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037013 | 0.87 | KDM4E (0.56) | ALDH1A1KDM4ELMNASLC9A1POLB | |
| SCHEMBL27330464 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAPOLBL3MBTL1 | |
| SCHEMBL27330465 | 0.81 | KDM4E (0.58) | ALDH1A1KDM4ELMNAPOLBL3MBTL1 | |
| SCHEMBL3030650 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNASLC9A1POLB | |
| SCHEMBL2557304 | 0.77 | KDM4E (0.65) | ALDH1A1KDM4ELMNAPOLBL3MBTL1 | |
| SCHEMBL3042946 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4ELMNASLC9A1POLB | |
| SCHEMBL2321506 | 0.76 | KDM4E (0.58) | ALDH1A1KDM4ELMNASLC9A1POLB | |
| SCHEMBL6010187 | 0.74 | SLC9A1 (0.50) | ALDH1A1KDM4ELMNASLC9A1POLB | |
| SCHEMBL3043067 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNASLC9A1POLB | |
| SCHEMBL2319080 | 0.74 | KDM4E (0.60) | ALDH1A1KDM4ELMNAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |