Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009898 | 1.00 | HTT (0.43) | HTTALDH1A1KMT2ALMNAMITF | |
| SCHEMBL6009893 | 1.00 | HTT (0.43) | HTTALDH1A1KMT2ALMNAMITF | |
| SCHEMBL355211 | 0.86 | SMN1; SMN2 (0.40) | KMT2ALMNAKDM4EHTR1AHTR7 | |
| SCHEMBL13330197 | 0.86 | LMNA (0.39) | HTTALDH1A1KMT2ALMNAHTR1A | |
| SCHEMBL353936 | 0.86 | SMN1; SMN2 (0.40) | KMT2ALMNAKDM4EHTR1AHTR7 | |
| SCHEMBL13330232 | 0.86 | LMNA (0.39) | HTTALDH1A1KMT2ALMNAHTR1A | |
| SCHEMBL353073 | 0.85 | GABBR2 (0.42) | HTTALDH1A1KMT2ALMNAHTR1A | |
| SCHEMBL355152 | 0.85 | SMN1; SMN2 (0.40) | ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL355588 | 0.85 | SMN1; SMN2 (0.40) | ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL354128 | 0.85 | GABBR2 (0.42) | HTTALDH1A1KMT2ALMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | APP, PSEN1, TTR | HTT 16/4885ALDH1A1 1915/4885KMT2A 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.