SCHEMBL600996

SCHEMBL600996

S=C1C=CC=C2C1=Nc1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.37
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
APAF1 O14727 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
TSHR P16473 1/20 0.33
HK1 P19367 1/20 0.33
GALK1 P51570 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
CCR6 P51684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8807286 0.79 IDO1 (0.44) IDO1MEN1ALDH1A1LMNAMAPT
SCHEMBL29350249 0.79 MAPT (0.39) IDO1MEN1ALDH1A1LMNAMAPT
SCHEMBL1506868 0.79 MAPT (0.39) IDO1MEN1ALDH1A1LMNAMAPT
SCHEMBL3302641 0.79 IDO1 (0.41) IDO1MEN1ALDH1A1LMNAMAPT
SCHEMBL29508369 0.79 IDO1 (0.37) IDO1MEN1ALDH1A1LMNAMAPT
Hydrochloric Acid SCHEMBL31604161 0.77 MAPT (0.38) IDO1MEN1ALDH1A1LMNAMAPT
SCHEMBL19283281 0.76 IDO1 (0.46) IDO1MEN1ALDH1A1LMNAMAPT
SCHEMBL25402538 0.75 IDO1 (0.34) IDO1MEN1ALDH1A1LMNAMAPT
SCHEMBL4749346 0.75 IDO1 (0.34) IDO1MEN1ALDH1A1LMNAMAPT
SCHEMBL28337014 0.75 IDO1 (0.34) IDO1MEN1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230088353-A1 ELECTROCHROMIC DEVICE AND METHOD FOR PRODUCING THE SAME FRESHAPE SA (CH) 2023-03-23 US claimed
EP-4121816-A1 ELECTROCHROMIC DEVICE AND METHOD FOR PRODUCING THE SAME Freshape SA (CH) 2023-01-25 EP claimed
WO-2021185999-A1 ELECTROCHROMIC DEVICE AND METHOD FOR PRODUCING THE SAME H.GLASS SA (CH) 2021-09-23 WO claimed
CN-104530007-A Preparation method of mono-substituted carbazolyl sulfide compound UNIV HUNAN 2015-04-22 CN claimed
US-20240152047-A1 HIGH REFRACTIVE INDEX MATERIALS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-05-09 US disclosed
CN-117866195-A High refractive index material 罗门哈斯电子材料有限责任公司 2024-04-12 CN disclosed
CN-116601157-A Sulfur-containing compounds for organic electroluminescent devices 默克专利有限公司 2023-08-15 CN disclosed
CN-111683930-B Novel isoxazole compound or salt thereof 日本欧爱特农业科技株式会社 2023-06-27 CN disclosed
US-20230088353-A1 ELECTROCHROMIC DEVICE AND METHOD FOR PRODUCING THE SAME FRESHAPE SA (CH) 2023-03-23 US disclosed
EP-4121816-A1 ELECTROCHROMIC DEVICE AND METHOD FOR PRODUCING THE SAME Freshape SA (CH) 2023-01-25 EP disclosed
WO-2021209645-A1 COMPOSITION FOR TREATING KERATIN TISSUE PVAC MEDICAL TECHNOLOGIES LTD (CY) 2021-10-21 WO disclosed
WO-2021185999-A1 ELECTROCHROMIC DEVICE AND METHOD FOR PRODUCING THE SAME H.GLASS SA (CH) 2021-09-23 WO disclosed
WO-2020149596-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME 주식회사 엘지화학 2020-07-23 WO disclosed
US-20170096426-A1 Novel Tricyclic Modulators of Cannabinoid Receptors THE UNIV OF MONTANA (US) 2017-04-06 US disclosed
CN-104530007-A Preparation method of mono-substituted carbazolyl sulfide compound UNIV HUNAN 2015-04-22 CN disclosed
US-20120039804-A1 Novel Tricyclic Modulators of Cannabinoid Receptors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2012-02-16 US disclosed
US-20030165772-A1 Negative resist composition FUJI PHOTO FILM CO., LTD. 2003-09-04 US disclosed
US-4035383-A Eutectic process for preparing polychloro copper phthalocyanine E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120039804-A1 Novel Tricyclic Modulators of Cannabinoid Receptors CNR1, CNR2, OPRL1 IDO1 671/4885MEN1 3607/4885ALDH1A1 4037/4885
US-20170096426-A1 Novel Tricyclic Modulators of Cannabinoid Receptors CNR1, CNR2, OPRL1 IDO1 671/4885MEN1 3607/4885ALDH1A1 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.