SCHEMBL8807286

SCHEMBL8807286

N=C1C=CC=C2C1=Nc1ccccc12

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.44
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
APAF1 O14727 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
HK1 P19367 1/20 0.33
GALK1 P51570 1/20 0.33
KMT2A Q03164 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350249 0.79 MAPT (0.39) IDO1KDM4EMEN1APAF1ALDH1A1
SCHEMBL600996 0.79 IDO1 (0.37) IDO1KDM4EMEN1APAF1ALDH1A1
SCHEMBL29508369 0.79 IDO1 (0.37) IDO1KDM4EMEN1APAF1ALDH1A1
SCHEMBL3302641 0.79 IDO1 (0.41) IDO1KDM4EMEN1APAF1ALDH1A1
SCHEMBL1506868 0.79 MAPT (0.39) IDO1KDM4EMEN1APAF1ALDH1A1
Hydrochloric Acid SCHEMBL31604161 0.77 MAPT (0.38) IDO1KDM4EMEN1APAF1ALDH1A1
SCHEMBL19283281 0.76 IDO1 (0.46) IDO1KDM4EMEN1APAF1ALDH1A1
SCHEMBL25402538 0.75 IDO1 (0.34) IDO1KDM4EMEN1APAF1ALDH1A1
SCHEMBL5487313 0.75 IDO1 (0.34) IDO1KDM4EMEN1APAF1ALDH1A1
SCHEMBL4749346 0.75 IDO1 (0.34) IDO1KDM4EMEN1APAF1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9012555-A None JP disclosed
CN-111087341-B Carbazolyl Schiff base fluorescent material 浙江华显光电科技有限公司 2023-11-10 CN disclosed
CN-113840606-A Treatment of cancer by administration of KRAS inhibitors 美国安进公司 2021-12-24 CN disclosed
CN-111087341-A Carbazolyl Schiff base fluorescent material 浙江华显光电科技有限公司 2020-05-01 CN disclosed
JP-H0912555-A NITRATED AZAFLUORENONE DERIVATIVE, NITRATED AZAFLUORENONEIMINE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITA IND CO LTD 1997-01-14 JP disclosed