Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 4/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350249 | 1.00 | MAPT (0.39) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL31604161 | 0.98 | MAPT (0.38) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| Sulfuric Acid SCHEMBL10962183 | 0.92 | ALDH1A1 (0.41) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL29636237 | 0.90 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL28324117 | 0.90 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL25242921 | 0.79 | MAOA (0.34) | MAOAMAOBCDC25B | |
| SCHEMBL29508369 | 0.79 | IDO1 (0.37) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL3302641 | 0.79 | IDO1 (0.41) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8807286 | 0.79 | IDO1 (0.44) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL600996 | 0.79 | IDO1 (0.37) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041248-B | Carbazole derivative with anticancer activity and preparation method and application thereof | 成都摩诃大龙医药科技有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-116041248-A | Carbazole derivative with anticancer activity and preparation method and application thereof | 成都摩诃大龙医药科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-116041333-A | Carbazole derivative with antimicrobial activity and preparation method and application thereof | 成都摩诃大龙医药科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-114395112-A | Hydrophobic block-containing polycarbazole anion exchange membrane and preparation method thereof | 北京化工大学 | 2022-04-26 | — | — | CN | claimed |
| CN-110317172-B | Azafluorenone derivative and preparation method and application thereof | 广东工业大学 | 2020-11-10 | — | — | CN | claimed |
| CN-105924450-B | Synthesis method of azafluorene spiro-aromatic hydrocarbon | 南京邮电大学 | 2020-05-15 | — | — | CN | claimed |
| US-8702815-B2 | Cyanoborate, fluoroalkylphosphate, fluoroalkylborate or imide dyes | MERCK PATENT GMBH (DE) | 2014-04-22 | — | — | US | claimed |
| EP-2292700-B1 | Cyanoborate dyes | MERCK PATENT GMBH (DE) | 2011-11-02 | — | — | EP | claimed |
| US-20110190480-A1 | CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES | IGNATYEV NIKOLAI MYKOLA | 2011-08-04 | — | — | US | claimed |
| EP-1660591-B1 | CATIONIC FLUOROALKYL-PHOSPHATE DYES | MERCK PATENT GMBH (DE) | 2010-10-27 | — | — | EP | claimed |
| US-20080275224-A1 | Cyanoborate, Fluoroalkylphosphate, Fluoroalkylborate or Imide Dyes | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | claimed |
| US-20070197797-A1 | Compounds and methods for carbazole synthesis | ROCHE COLORADO CORPORATION | 2007-08-23 | — | — | US | claimed |
| EP-1198457-B1 | QUATERNIZED AZAFLUORENONES AND THEIR USE IN AGENTS FOR DYING FIBERS CONTAINING KERATIN | HENKEL KGAA (DE) | 2005-12-14 | — | — | EP | claimed |
| CN-1045438-C | 4H carbazoleone Mannich base and its synthesizing method and application | SHANGHAI INST ORGANIC CHEM (CN) | 1999-10-06 | — | — | CN | claimed |
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | claimed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | claimed |
| JP-8151370-A | — | — | None | — | — | JP | disclosed |
| US-6444385-B1 | — | — | None | — | — | US | disclosed |
| EP-0028270-B1 | PYRAZINO-CARBAZOLES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CASSELLA Aktiengesellschaft (DE) | 1983-02-16 | — | — | EP | disclosed |
| EP-0028270-A1 | Pyrazino-carbazoles, process for their preparation and pharmaceutical compositions containing them | CASSELLA Aktiengesellschaft (DE) | 1981-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190480-A1 | CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES | ZAP70, MYLK3, KIT | MAPT 3351/4885ALDH1A1 1799/4885LMNA 871/4885 |
| US-20080275224-A1 | Cyanoborate, Fluoroalkylphosphate, Fluoroalkylborate or Imide Dyes | ZAP70, MYLK3, KIT | MAPT 3351/4885ALDH1A1 1799/4885LMNA 871/4885 |
| US-20070197797-A1 | Compounds and methods for carbazole synthesis | CNR2, CNR1, CYP2J2 | MAPT 4320/4885ALDH1A1 393/4885LMNA 1545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.