⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27391834 | 1.00 | — | — | |
| SCHEMBL18023464 | 0.82 | SMN1; SMN2 (0.49) | — | |
| SCHEMBL6859346 | 0.82 | POLB (0.51) | — | |
| SCHEMBL27391819 | 0.81 | — | — | |
| SCHEMBL875553 | 0.80 | — | — | |
| SCHEMBL7604693 | 0.80 | — | — | |
| SCHEMBL5141952 | 0.78 | — | — | |
| SCHEMBL5141953 | 0.78 | — | — | |
| SCHEMBL18773779 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL6010070 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112918-A1 | RNA DEGRADERS AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2022132609-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2022-06-23 | — | — | WO | disclosed |
| EP-2780039-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-2780039-B1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2017-11-29 | — | — | EP | disclosed |
| EP-0895470-B1 | AGENT AND METHOD FOR PERMANENTLY SHAPING THE HAIR, BASED ON N-BRANCHED-CHAIN ALKYL-SUBSTITUTED MERCAPTO ACETAMIDES | WELLA AG (DE) | 2006-09-20 | — | — | EP | disclosed |
| EP-1639992-A2 | Process for preparing of N-branched-chain alkyl-substituted mercapto acetamides | Wella Aktiengesellschaft (DE) | 2006-03-29 | — | — | EP | disclosed |
| US-6153180-A | AN AGENT FOR THE PERMANENT SHAPING OF HAIR, CONTAINS AS ACTIVE KERATIN-REDUCING SUBSTANCE A N-BRANCHED CHAIN ALKYL SUBSTITUTED MERCAPTO-METHYLACETAMIDE COMPOUND | WELLA AKTIENGESELLSCHAFT (DE) | 2000-11-28 | — | — | US | disclosed |
| EP-0895470-A1 | AGENT AND METHOD FOR PERMANENTLY SHAPING THE HAIR, BASED ON N-BRANCHED-CHAIN ALKYL-SUBSTITUTED MERCAPTO ACETAMIDES AND PROCESS FOR THEIR PREPARATION | Wella Aktiengesellschaft (DE) | 1999-02-10 | — | — | EP | disclosed |
| WO-1998030197-A1 | AGENT AND METHOD FOR PERMANENTLY SHAPING THE HAIR, BASED ON N-BRANCHED-CHAIN ALKYL-SUBSTITUTED MERCAPTO ACETAMIDES AND PROCESS FOR THEIR PREPARATION | WELLA AKTIENGESELLSCHAFT (DE) | 1998-07-16 | — | — | WO | disclosed |