Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847485 | 0.82 | POLB (0.55) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL27391834 | 0.82 | — | — | |
| SCHEMBL16298854 | 0.82 | POLB (0.55) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL13416265 | 0.82 | POLB (0.55) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL8848209 | 0.82 | POLB (0.55) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL6010086 | 0.82 | — | — | |
| SCHEMBL5141993 | 0.80 | POLB (0.53) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL5143891 | 0.80 | POLB (0.53) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL24235744 | 0.78 | POLB (0.51) | POLBKMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL21377157 | 0.78 | POLB (0.51) | POLBKMT2ALMNATHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10605810-B2 | Pincers comprising antibody and aptamer conjugated via a linker which binds to the same target material and use thereof | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2020-03-31 | — | — | US | disclosed |
| US-20170028070-A1 | PINCERS COMPRISING ANTIBODY AND APTAMER CONJUGATED VIA A LINKER WHICH BINDS TO THE SAME TARGET MATERIAL AND USE THEREOF | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2017-02-02 | — | — | US | disclosed |
| US-6790971-B1 | AMIDE OR CARBAMATE FUNCTION AT 11 BETA-POSITION; CLAIMED 3-ONE-DIENE INTERMEDIATE HAS HYDROXYMETHYLALKYL GROUP ON 11 POSITION; ANTIPROGESTOMIMETIC; HORMONE-DEPENDENT TUMORS; ANIMAL HUSBANDRY | AVENTIS PHARMA S.A. (FR) | 2004-09-14 | — | — | US | disclosed |
| EP-0471612-B1 | New steroids having an amide substituted group in the 11-beta position, their preparation, their use as medicines and pharmaceutical composition thereof | ROUSSEL UCLAF (FR) | 1998-01-28 | — | — | EP | disclosed |
| US-5707982-A | ANTITUMOR | ROUSSEL UCLAF (FR) | 1998-01-13 | — | — | US | disclosed |
| EP-0471612-A2 | New steroids having an amide substituted group in the 11-beta position, their preparation, their use as medicines and pharmaceutical composition thereof | ROUSSEL UCLAF (FR) | 1992-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170028070-A1 | PINCERS COMPRISING ANTIBODY AND APTAMER CONJUGATED VIA A LINKER WHICH BINDS TO THE SAME TARGET MATERIAL AND USE THEREOF | ILK, PAICS, AURKC | POLB 2296/4885KMT2A 1147/4885LMNA 124/4885 |
| US-10605810-B2 | Pincers comprising antibody and aptamer conjugated via a linker which binds to the same target material and use thereof | ILK, PAICS, AURKC | POLB 2296/4885KMT2A 1147/4885LMNA 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.