Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.57 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | LDHB | P07195 | 1/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697667 | 0.83 | HPGD (0.65) | SLC9A1HPGDHTTALDH1A1POLB | |
| SCHEMBL27330465 | 0.81 | KDM4E (0.58) | PIK3CAPIK3CGHPGDHTTALDH1A1 | |
| SCHEMBL1728691 | 0.80 | MAPT (0.64) | HPGDHTTALDH1A1POLBMAPT | |
| SCHEMBL3030714 | 0.77 | ALDH1A1 (0.50) | HPGDHTTALDH1A1POLBMAPT | |
| SCHEMBL6009501 | 0.77 | ALDH1A1 (0.62) | SLC9A1HPGDHTTERN1ALDH1A1 | |
| SCHEMBL14314321 | 0.77 | TYR (0.47) | PIK3CAPIK3CGHPGDHTTLDHA | |
| SCHEMBL3033242 | 0.77 | LDHA (0.46) | PIK3CAPIK3CGHPGDLDHALDHB | |
| SCHEMBL3038244 | 0.76 | KDM4E (0.63) | PIK3CAPIK3CGHPGDLDHALDHB | |
| SCHEMBL17354460 | 0.76 | MAPT (0.67) | PIK3CAPIK3CGHPGDLDHALDHB | |
| SCHEMBL3028708 | 0.74 | ESR1 (0.69) | PIK3CAPIK3CGHPGDLDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |