Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010888 | 0.87 | GPR35 (0.61) | GPR35ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL17744644 | 0.84 | GPR35 (0.52) | GPR35ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9500870 | 0.81 | GPR35 (0.68) | GPR35ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL17744647 | 0.81 | GPR35 (0.49) | GPR35ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL10981893 | 0.80 | GPR35 (0.47) | GPR35ALDH1A1TDP1SMN1; SMN2CYP3A4 | |
| SCHEMBL5041429 | 0.79 | GPR35 (0.53) | GPR35ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL38652666 | 0.77 | TDP1 (0.52) | GPR35ALDH1A1TDP1SMN1; SMN2CYP3A4 | |
| SCHEMBL4544555 | 0.77 | GPR35 (0.74) | GPR35ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5408193 | 0.77 | GPR35 (0.50) | GPR35ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL30954158 | 0.77 | CYP1A2 (0.56) | GPR35ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045516-B1 | Benzoxazole derivatives and drugs containing the same as the active ingredient | KOICHI SHUDO (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1134220-B1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | SHUDO KOICHI (JP) | 2004-08-18 | — | — | EP | disclosed |
| CN-1333771-A | Benzoxazole derivative and drug containing the same as active ingredient | MEIJI SEIKA KAISHA (JP) | 2002-01-30 | — | — | CN | disclosed |
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |