Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010818 | 0.87 | GPR35 (0.57) | GPR35ALDH1A1TDP1MEN1MAPT | |
| SCHEMBL8044810 | 0.85 | GPR35 (0.61) | GPR35ALDH1A1TDP1MEN1MAPT | |
| SCHEMBL5041429 | 0.85 | GPR35 (0.53) | GPR35ALDH1A1TDP1MEN1MAPT | |
| SCHEMBL10603471 | 0.82 | GPR35 (0.52) | GPR35ALDH1A1TDP1SMN1; SMN2CYP3A4 | |
| SCHEMBL31053019 | 0.82 | GPR35 (0.74) | GPR35ALDH1A1TDP1MEN1MAPT | |
| SCHEMBL17744644 | 0.82 | GPR35 (0.52) | GPR35ALDH1A1TDP1MEN1MAPT | |
| SCHEMBL9112380 | 0.80 | GPR35 (0.83) | GPR35ALDH1A1TDP1MEN1MAPT | |
| SCHEMBL3234929 | 0.79 | TSHR (0.55) | GPR35ALDH1A1TDP1CYP3A4CYP1A2 | |
| SCHEMBL8083889 | 0.79 | GPR35 (0.58) | GPR35ALDH1A1TDP1MEN1MAPT | |
| SCHEMBL10981893 | 0.79 | GPR35 (0.47) | GPR35ALDH1A1TDP1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038328-A | PROCESS FOR PREPARING 2-NITRO-4,6-DICHLORO-5-METHYLPHENOL | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | claimed |
| JP-57067543-A | — | — | None | — | — | JP | disclosed |
| JP-54073742-A | — | — | None | — | — | JP | disclosed |
| JP-5208938-A | — | — | None | — | — | JP | disclosed |
| US-7045516-B1 | Benzoxazole derivatives and drugs containing the same as the active ingredient | KOICHI SHUDO (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1134220-B1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | SHUDO KOICHI (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-1137632-B1 | THIOUREA INHIBITORS OF HERPES VIRUSES | WYETH CORP (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-1137645-B1 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | WYETH CORP (US) | 2004-05-26 | — | — | EP | disclosed |
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |
| US-20030036653-A1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | AMERICAN HOME PRODUCTS CORPORATION | 2003-02-20 | — | — | US | disclosed |
| EP-0473464-A1 | Process for preparing 2-4-dichloro-3-alkyl-6-nitrophenols | TAOKA CHEMICAL CO., LTD (JP) | 1992-03-04 | — | — | EP | disclosed |
| WO-1991002717-A1 | PROCESS FOR PREPARING 5-CHLOR-2-HYDROXY-4-ALKYL-BENZENE-SULPHONIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-07 | — | — | WO | disclosed |
| EP-0175151-B1 | 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1989-01-18 | — | — | EP | disclosed |
| US-4670608-A | CATALYTIC CHLORINATION OF 1-ALKYL-4-NITROBENZENE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |
| EP-0175151-A1 | 2,4-Dichloro-3-alkyl-6-nitrophenols and process for their preparation | BAYER AG (DE) | 1986-03-26 | — | — | EP | disclosed |
| JP-S5767543-A | PREPARATION OF 2-AMINO-4,6-DICHLORO-5-METHYLPHENOL | YODOGAWA SEIYAKU KK | 1982-04-24 | — | — | JP | disclosed |
| JP-S5473742-A | PRODUCTION OF 2-NITRO-4,6-DICHLORO-5-METHYLPHENOL | SUMITOMO CHEM CO LTD | 1979-06-13 | — | — | JP | disclosed |
| US-4038328-A | PROCESS FOR PREPARING 2-NITRO-4,6-DICHLORO-5-METHYLPHENOL | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
| US-3903178-A | Method for preparing 2-nitro-4,6-dichloro-5-methylphenol | FUJI PHOTO FILM CO LTD | 1975-09-02 | — | — | US | disclosed |
| US-3903178-A | Method for preparing 2-nitro-4,6-dichloro-5-methylphenol | FUJI PHOTO FILM CO LTD | 1975-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036653-A1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | HAVCR2, CCR6, CXCR6 | GPR35 3002/4885ALDH1A1 3447/4885TDP1 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.