Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010844 | 0.85 | CHRNB2 (0.38) | HTR6MAOBCXCR4NCF1 | |
| SCHEMBL6010809 | 0.81 | F10 (0.44) | HTR6NCF1 | |
| Hydrochloric Acid SCHEMBL6010656 | 0.80 | F10 (0.43) | HTR6NCF1 | |
| SCHEMBL6010815 | 0.78 | CHRNB2 (0.39) | HTR6 | |
| SCHEMBL6010820 | 0.77 | HRH4 (0.46) | HTR6NCF1 | |
| SCHEMBL6010862 | 0.77 | HTR6 (0.40) | HTR6 | |
| Hydrochloric Acid SCHEMBL6010978 | 0.76 | HTR6 (0.39) | HTR6 | |
| SCHEMBL6010864 | 0.76 | CHRNB2 (0.43) | HTR6NCF1 | |
| SCHEMBL6010738 | 0.75 | HRH4 (0.45) | HTR6 | |
| SCHEMBL4158366 | 0.75 | CHRNB2 (0.42) | HTR6NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | claimed |
| US-7045516-B1 | Benzoxazole derivatives and drugs containing the same as the active ingredient | KOICHI SHUDO (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1134220-B1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | SHUDO KOICHI (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |